Paper Details

Paper Title

A Network of Conserved Synthetic Lethal Interactions for Exploration of Precision Cancer Therapy.

Paper Journal Title

Mol Cell

Paper Citation Count

Paper Publication Year

2016

Bio Mention

BLM, Cancer, HeLa cells, RAD17, TSG, cancer, checkpoint kinases, human, human cancer cells, human tumor suppressor genes, lethality, patient, topoisomerases, tumor, yeast

Mesh Descriptor

Antineoplastic Agents, Biomarkers, Tumor, Cell Cycle Proteins, Cell Proliferation, Cell Survival, Dose-Response Relationship, Drug, Female, Gene Expression Regulation, Fungal, Gene Expression Regulation, Neoplastic, Gene Regulatory Networks, Genes, Tumor Suppressor, Genetic Predisposition to Disease, HeLa Cells, Humans, Kaplan-Meier Estimate, Molecular Targeted Therapy, Mutation, Phenotype, Precision Medicine, Protein Interaction Maps, RNA Interference, RecQ Helicases, Saccharomyces cerevisiae, Saccharomyces cerevisiae Proteins, Signal Transduction, Synthetic Lethal Mutations, Time Factors, Transfection, Uterine Cervical Neoplasms

Author Name	Affiliation
Rohith Srivas	University of California San Diego
John Paul Shen	University of California San Diego, USA Moores Cancer Center
Chih-Cheng Yang	Sanford-Burnham-Prebys Medical Discovery Institute
Su Ming Sun	Leiden University Medical Center
Jianfeng Li	University of Pittsburgh, Mitchell Cancer Institute, University of South Alabama
Andrew M Gross	University of California
James Jensen	University of California
Katherine Licon	University of California San Diego
Ana Bojorquez-Gomez	University of California San Diego
Kristin Klepper	University of California San Diego
Justin K Huang	University of California
Daniel Pekin	University of California San Diego
Jia L Xu	University of California San Diego
Huwate Yeerna	University of California San Diego
Vignesh Sivaganesh	University of California San Diego
Leonie Kollenstart	Leiden University Medical Center
Haico van Attikum	Leiden University Medical Center
Pedro Aza-Blanc	Sanford-Burnham-Prebys Medical Discovery Institute
Robert W Sobol	University of Pittsburgh, Mitchell Cancer Institute, University of South Alabama
Trey Ideker (CM4AI)	University of California San Diego, USA Moores Cancer Center
Trey Ideker (CM4AI)	University of California San Diego, USA Moores Cancer Center

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