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Paper Details

CALR-mutated cells are vulnerable to combined inhibition of the proteasome and the endoplasmic reticulum stress response.
Leukemia
4
2023
-mutant LT-HSCs, -mutated cells, CALR, CALR-mutant, CALR-mutant hematopoietic stem cells, CALR-mutated cells, Calr, Calr-mutant, Calr-mutant LT-HSCs, Calr-mutant long-term HSCs, Calr-mutated HSCs, Cancer, HSCs, IRE1, JAK, MPL, MPN, STAT, XBP1, calreticulin, calreticulin (CALR) gene, megakaryocyte progenitors, megakaryocytic-lineage cells, mutant CALR, mutated gene, myeloproliferative neoplasms, thrombopoietin receptor, wild-type cells
Author NameAffiliation
Steven A CarrThe Broad Institute of MIT and Harvard
Steven A CarrThe Broad Institute of MIT and Harvard
F??tima Al-ShahrourSpanish National Cancer Research Centre (CNIO)
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