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Paper Details

Shh signaling protects Atoh1 from degradation mediated by the E3 ubiquitin ligase Huwe1 in neural precursors.
Dev Cell
60
2014
Atoh1, E3 ubiquitin ligase, GNPs, Huwe1, SHH, Shh, Sonic hedgehog, cancer, cerebellar granule, cerebellar granule neuron progenitors, malignant brain tumor, medulloblastoma, mouse, mouse SHH medulloblastoma, neural precursors, neuronal precursor, protein Atoh1, transcription factor
Animals, Basic Helix-Loop-Helix Transcription Factors, Cell Differentiation, Cells, Cultured, Cerebellar Neoplasms, Chromatography, Affinity, Female, Hedgehog Proteins, Humans, Male, Medulloblastoma, Mice, Mice, Inbred C57BL, Mice, Knockout, Neurons, Patched Receptors, Phosphorylation, Proteolysis, Receptors, Cell Surface, Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization, Stem Cells, Survival Rate, Tumor Suppressor Proteins, Ubiquitin-Protein Ligases
Author NameAffiliation
Antoine Forget (CM4AI)Institut Curie, CNRS UMR 3306, INSERM U1005, Centre Universitaire
Laure BihannicInstitut Curie, CNRS UMR 3306, INSERM U1005, Centre Universitaire
Sara Maria CignaInstitut Curie, CNRS UMR 3306, INSERM U1005, Centre Universitaire
Coralie LefevreInstitut Curie, CNRS UMR 3306, INSERM U1005, Centre Universitaire
Marc RemkeArthur and Sonia Labatt Brain Tumor Research Centre, Hospital for Sick Children, University of Toronto
Monia BarnatInstitut Curie, CNRS UMR 3306, INSERM U1005, Centre Universitaire
Sophie DodierInstitut Curie, CNRS UMR 3306, INSERM U1005, Centre Universitaire
Hamasseh ShirvaniInstitut Curie, CNRS UMR 3306, INSERM U1005, Centre Universitaire
Audrey L MercierInstitut Curie, CNRS UMR 3306, INSERM U1005, Centre Universitaire
Aurore MensahInstitut Curie, CNRS UMR 3306, INSERM U1005, Centre Universitaire
Mickael GarciaInstitut Curie
Sandrine HumbertInstitut Curie, CNRS UMR 3306, INSERM U1005, Centre Universitaire
Michael D TaylorArthur and Sonia Labatt Brain Tumor Research Centre, Hospital for Sick Children, University of Toronto
Michael D TaylorArthur and Sonia Labatt Brain Tumor Research Centre, Hospital for Sick Children, University of Toronto
Anna LasorellaInstitute for Cancer Genetics, Columbia University Medical Center
Olivier AyraultInstitut Curie, CNRS UMR 3306, INSERM U1005, Centre Universitaire
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