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Poly(adenosine diphosphate ribose) polymerase inhibitors induce autophagy-mediated drug resistance in ovarian cancer cells, xenografts, and patient-derived xenograft models.
Cancer
46
2020
-H2AX, AKT, ATG5, ATG7, ATM, H2AX, LC3, LC3I, LC3II, LYS05, OVCAR8 human ovarian cancer cell line, OVCAR8 xenografts, Olaparib, PARP, PDX, PTEN, Poly(adenosine diphosphate ribose), Poly(adenosine diphosphate ribose) polymerase, autophagosomes, cancer, cancer cells, chloroquine, human, hydroxychloroquine, mTOR, niraparib, olaparib, ovarian, ovarian cancer, ovarian cancer cells, ovarian cancers, oxygen, patient, patient-derived xenograft models, patients, rucaparib, small interfering RNA, talazoparib, wild-type BRCA

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