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Paper Details

ecDNA hubs drive cooperative intermolecular oncogene expression.
Nature
118
2021
BET, BET), BRD4, Extrachromosomal, Extrachromosomal DNA, JQ1, MYC, MYC-amplified colorectal cancer cell line, PVT1 promoter, bromodomain and extraterminal domain (, cancer, cancer cell types, cancers, chromosome2, cis-regulatory elements, colorectal cancer, ecDNA, ecDNA enhancers, ecDNA hubs, ecDNA-derived-oncogene, ecDNAs, human, oncogene, oncogene loci, oncogenes, primary tumours
Author NameAffiliation
Jens LuebeckUniversity of California
Jens LuebeckUniversity of California
M Ryan CorcesCenter for Personal Dynamic Regulomes, Stanford University School of Medicine
Jeffrey M GranjaCenter for Personal Dynamic Regulomes, Stanford University School of Medicine
Stefan MundlosMax Planck Institute for Molecular Genetics
Stefan MundlosInstitute for Medical and Human Genetics, Charite-Universitatsmedizin Berlin
Stefan MundlosBerlin-Brandenburg Center for Regenerative Therapies (BCRT), Charite-Universitatsmedizin Berlin
Vineet BafnaUniversity of California
Vineet BafnaUniversity of California
Anton G HenssenCharite-Universitatsmedizin Berlin
Anton G HenssenBerlin Institute of Health
Anton G Henssenand German Cancer Research Center DKFZ
Anton G HenssenExperimental and Clinical Research Center (ECRC), Max Delbruck Center for Molecular Medicine and Charite-Universitatsmedizin Berlin
Paul S MischelStanford University
Paul S MischelStanford University
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