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Paper Details

Modeling RAS phenotype in colorectal cancer uncovers novel molecular traits of RAS dependency and improves prediction of response to targeted agents in patients.
Clin Cancer Res
27
2014
Cancer, EGFR, FBXW7, FBXW7 mutation, KRAS, KRAS mutation, MAP-ERK kinase, MAP2K4, MAP2K4 mutation, MED12, MEK, RAS, RAS pathway, anti-EGF receptor, cell line, cell lines, cell panel, cetuximab, colorectal cancer, mouse, mouse xenografts, patient, patients, xenograft, xenografts
Author NameAffiliation
Justin GuinneyFred-Hutchinson Cancer Research Center
Justin GuinneyFred-Hutchinson Cancer Research Center
Jonathan R Dry
Stephen H FriendFred-Hutchinson Cancer Research Center
Pierre Laurent-PuigINSERM UMR-S, Universite Paris Descartes
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