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Paper Details

The pancreatic cancer immune tumor microenvironment is negatively remodeled by gemcitabine while TGF-β receptor plus dual checkpoint inhibition maintains antitumor immune cells.
Mol Carcinog
8
2022
CD8+, CTLA-4, GAL, GEM, M1 macrophage, PDA, Pancreatic ductal adenocarcinoma (PDA) tumors, TGF-, TGF-?, Transforming growth factor-, anti-PD-L1, antitumor M1 macrophages, antitumor immune cells, cancer, cytotoxic CD8+ T cell, cytotoxic CD8+ T cell subpopulation, galunisertib, gemcitabine, immune cell, mice, murine, murine PDA cells, pancreatic cancer, patients, tumor
Author NameAffiliation
David Neil HayesCenter for Cancer Research, College of Medicine, The University of Tennessee Health Science Center
David Neil HayesThe University of Tennessee Health Science Center
David Neil HayesCenter for Cancer Research, College of Medicine, The University of Tennessee Health Science Center
David Neil HayesThe University of Tennessee Health Science Center
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Release 1.2