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Paper Details

Cryo-EM structures of PI3Kα reveal conformational changes during inhibition and activation.
Proceedings of the National Academy of Sciences of the United States of America
12
2021
ABD, ATP, BYL-719, PI3K, PI3Ks, Phosphoinositide 3-kinases, SH3 domains, adaptor, adenosine triphosphate, cSH2, cancers, full-length PI3K, full-length PI3K dimer, heterodimer PI3K, niSH2 domain, p110, p110 domains, p85, p85 domains, phosphopeptide
Author NameAffiliation
Jonathan R HartThe Scripps Research Institute
Peter K VogtThe Scripps Research Institute
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