Skip to Main Content

Paper Details

Disordered methionine metabolism in MTAP/CDKN2A-deleted cancers leads to dependence on PRMT5.
Science
293
2016
-, 5-Methylthioadenosine, 5-Methylthioadenosine phosphorylase, CDKN2A, CDKN2A-deleted cancers, CDKN2A-deleted tumors, MTA, MTAP, MTAP gene, MTAP-deficient cell line, MTAP-deleted cancers, MTAP-deleted cells, MTAP-proficient cells, MTAP/, MTAP/CDKN2A-deleted cancers, MTAP/CDKN2A-deleted tumors, PRMT5, PRMT5 methyltransferase, arginine, cancer, cancer cell line models, cancer cells, cancers, human, methionine, methylthioadenosine, proficient cells, protein arginine methyltransferase PRMT5, short hairpin RNA, tumor, tumor suppressor gene CDKN2A
Author NameAffiliation
Kavitha VenkatesanNovartis Institutes for Biomedical Research
Jianjun YuNovartis Institutes for Biomedical Research
Jeffery A PorterNovartis Institutes for Biomedical Research
William R SellersNovartis Institutes for Biomedical Research
  • 1 - 4

Datasets

Release 1.2