Paper Details

Paper Title

Exposure of iPSC-derived human microglia to brain substrates enables the generation and manipulation of diverse transcriptional states in vitro.

Paper Journal Title

Nat Immunol

Paper Citation Count

Paper Publication Year

2023

Bio Mention

Alzheimer's disease, MITF, Microglia, amyloid-beta fibrils, apoptotic neurons, disease-associated microglia, gene signatures, highly phagocytic state, human, human brain microglia, human microglia, human microglial states, human stem-cell-differentiated microglia, iPSC, iPSC-derived human microglia, macrophages, neurodegenerative diseases, synaptosomes

Mesh Descriptor

Author Name	Affiliation
Martine Therrien	Stanley Center for Psychiatric Research, The Broad Institute of MIT and Harvard
Martine Therrien	Harvard Medical School
Martine Therrien	Boston Children's Hospital
Sarah Murphy	Boston Children's Hospital
Kevin Eggan	Stanley Center for Psychiatric Research, The Broad Institute of MIT and Harvard
Kevin Eggan	Harvard University
Nir Hacohen	Broad Institute of MIT and Harvard Cambridge
Nir Hacohen	Harvard Medical School
Nir Hacohen	Center for Cancer Research, Massachusetts General Hospital
Nir Hacohen	Broad Institute of MIT and Harvard Cambridge
Nir Hacohen	Center for Cancer Research, Massachusetts General Hospital
Nir Hacohen	Harvard Medical School
Bradley E Bernstein	Broad Institute of MIT and Harvard Cambridge
Bradley E Bernstein	Harvard Medical School
Bradley E Bernstein	Harvard Medical School
Bradley E Bernstein	Dana-Farber Cancer Institute
Bradley E Bernstein	Broad Institute of MIT and Harvard Cambridge
Bradley E Bernstein	Dana-Farber Cancer Institute
Bradley E Bernstein	Harvard Medical School
Bradley E Bernstein	Harvard Medical School
Christopher K Glass	University of California San Diego
Christopher K Glass	University of California San Diego
Feng Zhang	Broad Institute of MIT and Harvard Cambridge
Feng Zhang
Feng Zhang	Howard Hughes Medical Institute
Feng Zhang
Feng Zhang	McGovern Institute for Brain Research at MIT
Feng Zhang	Broad Institute of MIT and Harvard Cambridge
Feng Zhang
Feng Zhang	Howard Hughes Medical Institute
Feng Zhang
Feng Zhang	McGovern Institute for Brain Research at MIT
Charles B Epstein	Broad Institute of MIT and Harvard Cambridge
Evan Z Macosko	Stanley Center for Psychiatric Research, The Broad Institute of MIT and Harvard
Evan Z Macosko	Massachusetts General Hospital
Beth Stevens	Stanley Center for Psychiatric Research, The Broad Institute of MIT and Harvard
Beth Stevens	Boston Children's Hospital
Beth Stevens	Harvard Medical School
Beth Stevens	Broad Institute of MIT and Harvard Cambridge
Beth Stevens	Howard Hughes Medical Institute

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