Skip to Main Content

Paper Details

Neutralization-guided design of HIV-1 envelope trimers with high affinity for the unmutated common ancestor of CH235 lineage CD4bs broadly neutralizing antibodies.
PLoS Pathogens
38
2019
CD4 binding site, CD4bs, CD4bs bnAbs, CDR, CDR L3, CH235, CH235 UCA, CH235 bnAb, CH235 lineage, Env loops, Env mutations, Env trimers, HCDR3 regions, HIV, HIV-1, HIV-1 envelope glycoprotein, Man5, Man5-enriched CH505.N279K.G458Y.SOSIP.664, N, N279K, SOSIP., V5, VH1, VH1-46, antibody light chain, bnAb, germline
Author NameAffiliation
Celia C LaBrancheDuke University Medical Center
Tongqing ZhouVaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health
Kevin WieheDuke Human Vaccine Institute, Duke University Medical Center
Kevin WieheDuke University Medical Center
Bette KorberLos Alamos National Laboratory
Peter D KwongVaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health
John R MascolaVaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health
David C MontefioriDuke University Medical Center
David C MontefioriDuke Human Vaccine Institute, Duke University Medical Center
  • 1 - 9

Datasets

Release 1.2