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Paper Details

DNA repair deficiency sensitizes lung cancer cells to NAD+ biosynthesis blockade.
J Clin Invest
18
2018
-WT cells, -deficient cells, DNA, DNA repair deficiency, ERCC1, ERCC1 deficiency, ERCC1-WT cells, ERCC1-deficient, ERCC1-deficient NSCLC, ERCC1-deficient NSCLC cell, ERCC1-deficient cells, Excision repair cross-complementation group 1, Excision repair cross-complementation group 1 (ERCC1) deficiency, NAD+, NAD+ biosynthetic enzyme, NAMPT, NSCLC, NSCLC models, NSCLC samples, Synthetic lethality, cancer, lung cancer, lung cancer cells, nicotinamide, nicotinamide phosphoribosyltransferase, non-small-cell lung cancer, vitro - ERCC1-deficient
Author NameAffiliation
Mehdi TouatInserm U, Universite Paris-Saclay
Mehdi TouatInserm U7, CNRS UMR 7225, Sorbonne Universites, UPMC Universite Paris 06 UMRS7, Institut du Cerveau et de la Moelle Epiniere
Mehdi TouatUniversite Paris-Saclay
Alan AshworthUCSF Helen Diller Family Comprehensive Cancer Center
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