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Paper Details

Phase 3 Safety and Efficacy of AZD1222 (ChAdOx1 nCoV-19) Covid-19 Vaccine.
N Engl J Med
399
2021
AZD1222, Covid-19, SARS-CoV, SARS-CoV-2, SARS-CoV-2 spike protein, coronavirus, coronavirus disease, nucleocapsid antibody, participants, severe acute respiratory syndrome coronavirus
Author NameAffiliation
Mark J MulliganFrom the University of Rochester School of Medicine and Dentistry (A.R.F., and Vagelos College of Physicians and Surgeons, New York Presbyterian Columbia University Irving Medical Center, Division of Infectious Diseases (M.E.S.) and the New York University Vaccine Center (M.J.M.), and Clinical Development, the Walter Reed Army Institute of Research, the University of Maryland School of Medicine (K.M.N.) and the Johns Hopkins Bloomberg School of Public Health (A.D.), and the National Institute of Allergy and Infectious Diseases, National Institutes of Health, M.C.N.) - all in Maryland the University of Washington (L.C., W.H.) and the Fred Hutchinson Cancer Research Center (L.C., Seattle HealthPartners Institute, Lake Worth Beach (L.B.) - both in Florida Hassman Research Institute, NJ (M.H.) the University of California San Diego, the Lundquist Institute at Harbor-university of california los angeles Medical Center, Jr. Hospital of Cook County, Chicago (T.O.) Instituto de Ciencias Biomedicas, Facultad de Medicina Universidad de Chile, Chile (S.L.V.) Clinica Internacional Sede Lima, Peru (A.G.B.) Clinical Research Partners, VA (R.C.) the University of Vermont Larner College of Medicine and UVM Medical Center, MT (J.P.) and the Rollins School of Public Health at Emory University
Edwin DeJesusFrom the University of Rochester School of Medicine and Dentistry (A.R.F., and Vagelos College of Physicians and Surgeons, New York Presbyterian Columbia University Irving Medical Center, Division of Infectious Diseases (M.E.S.) and the New York University Vaccine Center (M.J.M.), and Clinical Development, the Walter Reed Army Institute of Research, the University of Maryland School of Medicine (K.M.N.) and the Johns Hopkins Bloomberg School of Public Health (A.D.), and the National Institute of Allergy and Infectious Diseases, National Institutes of Health, M.C.N.) - all in Maryland the University of Washington (L.C., W.H.) and the Fred Hutchinson Cancer Research Center (L.C., Seattle HealthPartners Institute, Lake Worth Beach (L.B.) - both in Florida Hassman Research Institute, NJ (M.H.) the University of California San Diego, the Lundquist Institute at Harbor-university of california los angeles Medical Center, Jr. Hospital of Cook County, Chicago (T.O.) Instituto de Ciencias Biomedicas, Facultad de Medicina Universidad de Chile, Chile (S.L.V.) Clinica Internacional Sede Lima, Peru (A.G.B.) Clinical Research Partners, VA (R.C.) the University of Vermont Larner College of Medicine and UVM Medical Center, MT (J.P.) and the Rollins School of Public Health at Emory University
Susan J LittleFrom the University of Rochester School of Medicine and Dentistry (A.R.F., and Vagelos College of Physicians and Surgeons, New York Presbyterian Columbia University Irving Medical Center, Division of Infectious Diseases (M.E.S.) and the New York University Vaccine Center (M.J.M.), and Clinical Development, the Walter Reed Army Institute of Research, the University of Maryland School of Medicine (K.M.N.) and the Johns Hopkins Bloomberg School of Public Health (A.D.), and the National Institute of Allergy and Infectious Diseases, National Institutes of Health, M.C.N.) - all in Maryland the University of Washington (L.C., W.H.) and the Fred Hutchinson Cancer Research Center (L.C., Seattle HealthPartners Institute, Lake Worth Beach (L.B.) - both in Florida Hassman Research Institute, NJ (M.H.) the University of California San Diego, the Lundquist Institute at Harbor-university of california los angeles Medical Center, Jr. Hospital of Cook County, Chicago (T.O.) Instituto de Ciencias Biomedicas, Facultad de Medicina Universidad de Chile, Chile (S.L.V.) Clinica Internacional Sede Lima, Peru (A.G.B.) Clinical Research Partners, VA (R.C.) the University of Vermont Larner College of Medicine and UVM Medical Center, MT (J.P.) and the Rollins School of Public Health at Emory University
Eric S DaarFrom the University of Rochester School of Medicine and Dentistry (A.R.F., and Vagelos College of Physicians and Surgeons, New York Presbyterian Columbia University Irving Medical Center, Division of Infectious Diseases (M.E.S.) and the New York University Vaccine Center (M.J.M.), and Clinical Development, the Walter Reed Army Institute of Research, the University of Maryland School of Medicine (K.M.N.) and the Johns Hopkins Bloomberg School of Public Health (A.D.), and the National Institute of Allergy and Infectious Diseases, National Institutes of Health, M.C.N.) - all in Maryland the University of Washington (L.C., W.H.) and the Fred Hutchinson Cancer Research Center (L.C., Seattle HealthPartners Institute, Lake Worth Beach (L.B.) - both in Florida Hassman Research Institute, NJ (M.H.) the University of California San Diego, the Lundquist Institute at Harbor-university of california los angeles Medical Center, Jr. Hospital of Cook County, Chicago (T.O.) Instituto de Ciencias Biomedicas, Facultad de Medicina Universidad de Chile, Chile (S.L.V.) Clinica Internacional Sede Lima, Peru (A.G.B.) Clinical Research Partners, VA (R.C.) the University of Vermont Larner College of Medicine and UVM Medical Center, MT (J.P.) and the Rollins School of Public Health at Emory University
Larry M BushFrom the University of Rochester School of Medicine and Dentistry (A.R.F., and Vagelos College of Physicians and Surgeons, New York Presbyterian Columbia University Irving Medical Center, Division of Infectious Diseases (M.E.S.) and the New York University Vaccine Center (M.J.M.), and Clinical Development, the Walter Reed Army Institute of Research, the University of Maryland School of Medicine (K.M.N.) and the Johns Hopkins Bloomberg School of Public Health (A.D.), and the National Institute of Allergy and Infectious Diseases, National Institutes of Health, M.C.N.) - all in Maryland the University of Washington (L.C., W.H.) and the Fred Hutchinson Cancer Research Center (L.C., Seattle HealthPartners Institute, Lake Worth Beach (L.B.) - both in Florida Hassman Research Institute, NJ (M.H.) the University of California San Diego, the Lundquist Institute at Harbor-university of california los angeles Medical Center, Jr. Hospital of Cook County, Chicago (T.O.) Instituto de Ciencias Biomedicas, Facultad de Medicina Universidad de Chile, Chile (S.L.V.) Clinica Internacional Sede Lima, Peru (A.G.B.) Clinical Research Partners, VA (R.C.) the University of Vermont Larner College of Medicine and UVM Medical Center, MT (J.P.) and the Rollins School of Public Health at Emory University
Michael C KeeferFrom the University of Rochester School of Medicine and Dentistry (A.R.F., and Vagelos College of Physicians and Surgeons, New York Presbyterian Columbia University Irving Medical Center, Division of Infectious Diseases (M.E.S.) and the New York University Vaccine Center (M.J.M.), and Clinical Development, the Walter Reed Army Institute of Research, the University of Maryland School of Medicine (K.M.N.) and the Johns Hopkins Bloomberg School of Public Health (A.D.), and the National Institute of Allergy and Infectious Diseases, National Institutes of Health, M.C.N.) - all in Maryland the University of Washington (L.C., W.H.) and the Fred Hutchinson Cancer Research Center (L.C., Seattle HealthPartners Institute, Lake Worth Beach (L.B.) - both in Florida Hassman Research Institute, NJ (M.H.) the University of California San Diego, the Lundquist Institute at Harbor-university of california los angeles Medical Center, Jr. Hospital of Cook County, Chicago (T.O.) Instituto de Ciencias Biomedicas, Facultad de Medicina Universidad de Chile, Chile (S.L.V.) Clinica Internacional Sede Lima, Peru (A.G.B.) Clinical Research Partners, VA (R.C.) the University of Vermont Larner College of Medicine and UVM Medical Center, MT (J.P.) and the Rollins School of Public Health at Emory University
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Datasets

ClinicalTrials.govClinicalTrials.gov, a registry and results database of of privately and publicly funded clinical studies conducted around the world, is operated by the U.S. National Library of Medicine (NLM). Structured study information is provided, voluntarily or to meet legal and policy requirements, by the sponsor or investigator responsible for the research. NLM does not verify the scientific validity or relevance of the submitted information beyond a limited quality control review for apparent errors, deficiencies, or inconsistencies.Link
ClinicalTrials.govClinicalTrials.gov, a registry and results database of of privately and publicly funded clinical studies conducted around the world, is operated by the U.S. National Library of Medicine (NLM). Structured study information is provided, voluntarily or to meet legal and policy requirements, by the sponsor or investigator responsible for the research. NLM does not verify the scientific validity or relevance of the submitted information beyond a limited quality control review for apparent errors, deficiencies, or inconsistencies.Link
ClinicalTrials.govClinicalTrials.gov, a registry and results database of of privately and publicly funded clinical studies conducted around the world, is operated by the U.S. National Library of Medicine (NLM). Structured study information is provided, voluntarily or to meet legal and policy requirements, by the sponsor or investigator responsible for the research. NLM does not verify the scientific validity or relevance of the submitted information beyond a limited quality control review for apparent errors, deficiencies, or inconsistencies.Link
ClinicalTrials.govClinicalTrials.gov, a registry and results database of of privately and publicly funded clinical studies conducted around the world, is operated by the U.S. National Library of Medicine (NLM). Structured study information is provided, voluntarily or to meet legal and policy requirements, by the sponsor or investigator responsible for the research. NLM does not verify the scientific validity or relevance of the submitted information beyond a limited quality control review for apparent errors, deficiencies, or inconsistencies.Link
ClinicalTrials.govClinicalTrials.gov, a registry and results database of of privately and publicly funded clinical studies conducted around the world, is operated by the U.S. National Library of Medicine (NLM). Structured study information is provided, voluntarily or to meet legal and policy requirements, by the sponsor or investigator responsible for the research. NLM does not verify the scientific validity or relevance of the submitted information beyond a limited quality control review for apparent errors, deficiencies, or inconsistencies.Link
ClinicalTrials.govClinicalTrials.gov, a registry and results database of of privately and publicly funded clinical studies conducted around the world, is operated by the U.S. National Library of Medicine (NLM). Structured study information is provided, voluntarily or to meet legal and policy requirements, by the sponsor or investigator responsible for the research. NLM does not verify the scientific validity or relevance of the submitted information beyond a limited quality control review for apparent errors, deficiencies, or inconsistencies.Link
ClinicalTrials.govClinicalTrials.gov, a registry and results database of of privately and publicly funded clinical studies conducted around the world, is operated by the U.S. National Library of Medicine (NLM). Structured study information is provided, voluntarily or to meet legal and policy requirements, by the sponsor or investigator responsible for the research. NLM does not verify the scientific validity or relevance of the submitted information beyond a limited quality control review for apparent errors, deficiencies, or inconsistencies.Link
ClinicalTrials.govClinicalTrials.gov, a registry and results database of of privately and publicly funded clinical studies conducted around the world, is operated by the U.S. National Library of Medicine (NLM). Structured study information is provided, voluntarily or to meet legal and policy requirements, by the sponsor or investigator responsible for the research. NLM does not verify the scientific validity or relevance of the submitted information beyond a limited quality control review for apparent errors, deficiencies, or inconsistencies.Link
ClinicalTrials.govClinicalTrials.gov, a registry and results database of of privately and publicly funded clinical studies conducted around the world, is operated by the U.S. National Library of Medicine (NLM). Structured study information is provided, voluntarily or to meet legal and policy requirements, by the sponsor or investigator responsible for the research. NLM does not verify the scientific validity or relevance of the submitted information beyond a limited quality control review for apparent errors, deficiencies, or inconsistencies.Link
ClinicalTrials.govClinicalTrials.gov, a registry and results database of of privately and publicly funded clinical studies conducted around the world, is operated by the U.S. National Library of Medicine (NLM). Structured study information is provided, voluntarily or to meet legal and policy requirements, by the sponsor or investigator responsible for the research. NLM does not verify the scientific validity or relevance of the submitted information beyond a limited quality control review for apparent errors, deficiencies, or inconsistencies.Link
ClinicalTrials.govClinicalTrials.gov, a registry and results database of of privately and publicly funded clinical studies conducted around the world, is operated by the U.S. National Library of Medicine (NLM). Structured study information is provided, voluntarily or to meet legal and policy requirements, by the sponsor or investigator responsible for the research. NLM does not verify the scientific validity or relevance of the submitted information beyond a limited quality control review for apparent errors, deficiencies, or inconsistencies.Link
ClinicalTrials.govClinicalTrials.gov, a registry and results database of of privately and publicly funded clinical studies conducted around the world, is operated by the U.S. National Library of Medicine (NLM). Structured study information is provided, voluntarily or to meet legal and policy requirements, by the sponsor or investigator responsible for the research. NLM does not verify the scientific validity or relevance of the submitted information beyond a limited quality control review for apparent errors, deficiencies, or inconsistencies.Link
ClinicalTrials.govClinicalTrials.gov, a registry and results database of of privately and publicly funded clinical studies conducted around the world, is operated by the U.S. National Library of Medicine (NLM). Structured study information is provided, voluntarily or to meet legal and policy requirements, by the sponsor or investigator responsible for the research. NLM does not verify the scientific validity or relevance of the submitted information beyond a limited quality control review for apparent errors, deficiencies, or inconsistencies.Link
ClinicalTrials.govClinicalTrials.gov, a registry and results database of of privately and publicly funded clinical studies conducted around the world, is operated by the U.S. National Library of Medicine (NLM). Structured study information is provided, voluntarily or to meet legal and policy requirements, by the sponsor or investigator responsible for the research. NLM does not verify the scientific validity or relevance of the submitted information beyond a limited quality control review for apparent errors, deficiencies, or inconsistencies.Link
ClinicalTrials.govClinicalTrials.gov, a registry and results database of of privately and publicly funded clinical studies conducted around the world, is operated by the U.S. National Library of Medicine (NLM). Structured study information is provided, voluntarily or to meet legal and policy requirements, by the sponsor or investigator responsible for the research. NLM does not verify the scientific validity or relevance of the submitted information beyond a limited quality control review for apparent errors, deficiencies, or inconsistencies.Link