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Paper Details

Novel Targeting of DNA Methyltransferase Activity Inhibits Ewing Sarcoma Cell Proliferation and Enhances Tumor Cell Sensitivity to DNA Damaging Drugs by Activating the DNA Damage Response.
Front Endocrinol (Lausanne)
4
2022
DNA, DNA Methyltransferase, DNMT, DNMT1, DNMT1 enzyme, DNMTi, EWS, EWS tumor, Ewing Sarcoma, Ewing sarcoma, H2AX, MC3343, PARP, PARPi, Tumor, Tumor Cell, children, doxorubicin, epigenome, p53, p53 mutated cells, p53wt, p53wt cells, primary bone tumor, tumor
Author NameAffiliation
Oscar M TiradoBellvitge Biomedical Research Institute (IDIBELL)
Katia ScotlandiIRCCS Istituto Ortopedico Rizzoli
Katia ScotlandiIRCCS Istituto Ortopedico Rizzoli
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