Skip to Main Content

Paper Details

Partial inhibition of the overactivated Ku80-dependent DNA repair pathway rescues neurodegeneration in <i>C9ORF72</i>-ALS/FTD.
Proc Natl Acad Sci U S A
59
2019
ALS, Bax, C9ORF72, C9ORF72 iPSC-derived patient neurons, Cas9, DNA repair, Drosophila, FTD, G4C2), Ku80, P53, PUMA, amyotrophic lateral sclerosis, caspase-3, dipeptide, expanded G4C2 repeats, frontotemporal dementia, neurodegeneration, neurons, patient, patient neurons, poly(GR), retinal degeneration, small RNAs
Author NameAffiliation
Gopinath KrishnanUniversity of Massachusetts Medical School
Soojin LeeUniversity of Massachusetts Medical School
Giovanni CoppolaSemel Institute for Neuroscience and Human Behavior, David Geffen School of Medicine, University of California los angeles
Fen-Biao GaoUniversity of Massachusetts Medical School
  • 1 - 4

Datasets

Release 1.2