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Paper Details

Imipridone ONC212 activates orphan G protein-coupled receptor GPR132 and integrated stress response in acute myeloid leukemia.
Leukemia
37
2019
ABT, ABT-199, AML, AML initiating cells, BCL-2, G protein-coupled receptors, GPCR, GPCRs, GPR132, Gq, Imipridone, Imipridones, MCL-1, ONC201, ONC212, acute myeloid leukemia, antitumor, hematopoietic tumor, hematopoietic tumor cells, human, human acute myeloid leukemia (AML) cell lines, imipridone, mice, normal BM cells, orphan G protein-coupled receptor GPR132, orphan GPCR, orphan GPCR GPR132, patient, patient-derived AML cells, tumor
Author NameAffiliation
Neel S MadhukarInstitute for Computational Biomedicine
Ruiying ZhaoThe University of Texas MD Anderson Cancer Center
Mathew J GarnettWellcome Trust Sanger Institute
Ultan McDermottWellcome Trust Sanger Institute
Cyril H BenesMassachusetts General Hospital
Olivier ElementoInstitute for Computational Biomedicine
Olivier ElementoInstitute for Computational Biomedicine
Joshua E AllenInc.
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