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Paper Details

Synthesis and Biological Activities of 11- and 12-Substituted Benzophenanthridinone Derivatives as DNA Topoisomerase IB and Tyrosyl-DNA Phosphodiesterase 1 Inhibitors.
ChemMedChem
1
2023
11- and 12-Substituted Benzophenanthridinone, 116cells, DNA Topoisomerase IB, DNA phosphodiesterase 1, HCT, HCT-116cells, MCF-7, MCF-7/TDP1cells, TDP1, TDP1cc, TDP1cells, TOP1, TOP1cc, Tyrosyl-DNA Phosphodiesterase 1, benzophenanthridinone, topoisomerase IB, topotecan, tyrosyl
Author NameAffiliation
Yves PommierCenter for Cancer Research, National Cancer Institute, National Institutes of Health
Yves PommierCenter for Cancer Research, National Cancer Institute, National Institutes of Health
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Release 1.2