Paper Details

Paper Title

Pharmacological and Toxicological Properties of the Potent Oral <i>Î³</i>-Secretase Modulator BPN-15606.

Paper Journal Title

J Pharmacol Exp Ther

Paper Citation Count

Paper Publication Year

2017

Bio Mention

-secretase, A neuritic plaque, A37, A38, A40 peptide, A42, A42 peptide, AD, APP, Alzheimer's disease, BPN-15606, Notch, Secretase, amino-, as, carboxyl, carboxyl-terminal fragments, human, human neural cell culture model, hyperphosporylated tau, mice, mouse, neural, neurofibrillary, neurofibrillary tangles, pThr181 tau, rats, t-secretase

Mesh Descriptor

Author Name	Affiliation
Steven L Wagner	University of California, R.A.R.) Integrated Nonclinical Development Solutions, Pennsylvania (J.H.L.) and Genetics and Aging Research Unit, Massachusetts General Hospital
Kevin D Rynearson	University of California, R.A.R.) Integrated Nonclinical Development Solutions, Pennsylvania (J.H.L.) and Genetics and Aging Research Unit, Massachusetts General Hospital
Can Zhang	University of California, R.A.R.) Integrated Nonclinical Development Solutions, Pennsylvania (J.H.L.) and Genetics and Aging Research Unit, Massachusetts General Hospital
Phuong Nguyen	University of California, R.A.R.) Integrated Nonclinical Development Solutions, Pennsylvania (J.H.L.) and Genetics and Aging Research Unit, Massachusetts General Hospital
Phuong Nguyen	University of California, R.A.R.) Integrated Nonclinical Development Solutions, Pennsylvania (J.H.L.) and Genetics and Aging Research Unit, Massachusetts General Hospital
William C Mobley	University of California, R.A.R.) Integrated Nonclinical Development Solutions, Pennsylvania (J.H.L.) and Genetics and Aging Research Unit, Massachusetts General Hospital
Rudolph E Tanzi	University of California, R.A.R.) Integrated Nonclinical Development Solutions, Pennsylvania (J.H.L.) and Genetics and Aging Research Unit, Massachusetts General Hospital

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