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Paper Details

Lupus enhancer risk variant causes dysregulation of IRF8 through cooperative lncRNA and DNA methylation machinery.
Nat Commun
11
2022
AC092723.1, IRF8, IRF8 promoter, Lupus, Lupus enhancer risk variant, PU, TET1, autoimmune diseases, cell-type-specific enhancer, chromatin, enhancer RNA AC092723.1, gene targets, human, human genetic variants, lncRNA, lupus, lupus risk variants, non-coding risk variants, rs2280381
Author NameAffiliation
John B HarleyUS Department of Veterans Affairs Medical Center
Bahram NamjouCenter for Autoimmune Genomics and Etiology, Cincinnati Children's Hospital Medical Center
Leah C KottyanCenter for Autoimmune Genomics and Etiology, Cincinnati Children's Hospital Medical Center
Leah C KottyanUniversity of Cincinnati College of Medicine
Leah C KottyanCincinnati Children's Hospital Medical Center
Matthew T WeirauchCenter for Autoimmune Genomics and Etiology, Cincinnati Children's Hospital Medical Center
Matthew T WeirauchUniversity of Cincinnati College of Medicine
Matthew T WeirauchCincinnati Children's Hospital Medical Center
Matthew T WeirauchCincinnati Children's Hospital Medical Center
Matthew T WeirauchCenter for Autoimmune Genomics and Etiology, Cincinnati Children's Hospital Medical Center
Matthew T WeirauchUniversity of Cincinnati College of Medicine
Matthew T WeirauchCincinnati Children's Hospital Medical Center
Matthew T WeirauchCincinnati Children's Hospital Medical Center
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Release 1.2