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Paper Details

Triple-negative breast cancers with amplification of JAK2 at the 9p24 locus demonstrate JAK2-specific dependence.
Sci Transl Med
94
2016
/9p24, 9p24, 9p24 locus, JAK1, JAK1/2, JAK2, JAK2-amplified TNBCs, Janus kinase 2, Janus kinase 2 (JAK2) gene, STAT3, TNBC, TNBC cell lines, TNBCs, Triple, Triple-negative breast cancers, basal-like cancers, breast cancer, cancer, cancer stem cell-like cell population, malignancies, mammosphere, patient, patient-derived TNBC xenografts, patients, signal transducer and activator of transcription 3, triple-negative breast cancers, tumor
Author NameAffiliation
Justin M BalkoVanderbilt University, Vanderbilt-Ingram Cancer Center
Roman YelenskyFoundation Medicine
Vincent A MillerFoundation Medicine
David L RimmYale University
Jenny Chang-ClaudeHouston Methodist Cancer Center
Melinda E SandersVanderbilt-Ingram Cancer Center, Vanderbilt University
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Release 1.2