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Paper Details

Spectrum and prevalence of genetic predisposition in medulloblastoma: a retrospective genetic study and prospective validation in a clinical trial cohort.
Lancet Oncol
225
2018
APC, BC Cancer, BRCA2, Brain Tumour, CTNNB1 exon 3, Cancer, Childhood Cancer, Children, MBGroup3, MBGroup4, MBSHH, MBWNT, Medulloblastoma, PALB2, PTCH1, Patients, Pediatric Brain Tumor, SHH, SUFU, TP53, WNT, Whole-genome sequences, blood, blood samples, cancer, cancer predisposition genes, chromothripsis, consensus, exome sequences, genes, hereditary cancer, homologous recombination repair deficiency, medulloblastoma, medulloblastoma predisposition genes, patients, recombination repair deficiency, somatic, tumour
Author NameAffiliation
Sebastian M Waszak
Sebastian M Waszak
Paul A NorthcottGerman Cancer Research Center (DKFZ), St Jude Children's Research Hospital
Paul A NorthcottGerman Cancer Research Center (DKFZ), St Jude Children's Research Hospital
Ivo BuchhalterGerman Cancer Research Center
Ivo BuchhalterGerman Cancer Research Center
Giles W RobinsonSt Jude Children's Research Hospital
Giles W RobinsonSt Jude Children's Research Hospital
Laurence Brugi??res
David T W JonesGerman Cancer Research Center (DKFZ), Germany Hopp Children's Cancer Center at the NCT Heidelberg
David T W JonesGerman Cancer Research Center (DKFZ), Germany Hopp Children's Cancer Center at the NCT Heidelberg
Kristian W PajtlerHeidelberg University Hospital, German Cancer Research Center (DKFZ), Germany Hopp Children's Cancer Center at the NCT Heidelberg
Kristian W PajtlerHeidelberg University Hospital, German Cancer Research Center (DKFZ), Germany Hopp Children's Cancer Center at the NCT Heidelberg
Anca Sorana MorrissyCumming School of Medicine, University of Calgary, The Hospital for Sick Children
Marcel KoolGerman Cancer Research Center (DKFZ), Germany Hopp Children's Cancer Center at the NCT Heidelberg
Marcel KoolGerman Cancer Research Center (DKFZ), Germany Hopp Children's Cancer Center at the NCT Heidelberg
Dominik SturmHeidelberg University Hospital, German Cancer Research Center (DKFZ), Germany Hopp Children's Cancer Center at the NCT Heidelberg
Dominik SturmHeidelberg University Hospital, German Cancer Research Center (DKFZ), Germany Hopp Children's Cancer Center at the NCT Heidelberg
Lukas ChavezGerman Cancer Research Center (DKFZ)
Lukas ChavezGerman Cancer Research Center (DKFZ)
Sebastian BrabetzHeidelberg University Hospital, German Cancer Research Center (DKFZ), Germany Hopp Children's Cancer Center at the NCT Heidelberg
Sebastian BrabetzHeidelberg University Hospital, German Cancer Research Center (DKFZ), Germany Hopp Children's Cancer Center at the NCT Heidelberg
Maia Segura-Wang
Joachim WeischenfeldtRigshospitalet, University of Copenhagen
Joachim WeischenfeldtRigshospitalet, University of Copenhagen
Tobias Rausch
Xin ZhouSt Jude Children's Research Hospital
Xin ZhouSt Jude Children's Research Hospital
Chris LawerenzGerman Cancer Research Center
Chris LawerenzGerman Cancer Research Center
Jennifer A ChanUniversity of Calgary
Jennifer A ChanUniversity of Calgary
Pascale VarletSainte-Anne Hospital
Pascale VarletSainte-Anne Hospital
Daniel W FultsUniversity of Utah School of Medicine
Wies??awa GrajkowskaChildren's Memorial Health Institute
Nada JabadoMcGill University
Nada JabadoMcGill University
Suyash ShringarpureStanford University School of Medicine
Suyash ShringarpureStanford University School of Medicine
Francisco M De La VegaStanford University School of Medicine
Carlos D BustamanteStanford University School of Medicine
Carlos D BustamanteStanford University School of Medicine
Ho-Keung NgThe Chinese University of Hong Kong
Ho-Keung NgThe Chinese University of Hong Kong
Arie PerryDepartment of Pathology and Helen Diller Family Comprehensive Cancer Center, University of California san francisco
Arie PerryDepartment of Pathology and Helen Diller Family Comprehensive Cancer Center, University of California san francisco
Anne BendelChildren's Hospitals and Clinics of Minnesota
Daniel C BowersUniversity of Texas Southwestern Medical School
Daniel C BowersUniversity of Texas Southwestern Medical School
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Exome Aggregation Consortium61,486 unrelated exomesLink
Exome Aggregation Consortium61,486 unrelated exomesLink
Exome Aggregation Consortium61,486 unrelated exomesLink
Exome Aggregation Consortium61,486 unrelated exomesLink
Exome Aggregation Consortium61,486 unrelated exomesLink
Exome Aggregation Consortium61,486 unrelated exomesLink
Exome Aggregation Consortium61,486 unrelated exomesLink
Exome Aggregation Consortium61,486 unrelated exomesLink
Exome Aggregation Consortium61,486 unrelated exomesLink
Exome Aggregation Consortium61,486 unrelated exomesLink
Exome Aggregation Consortium61,486 unrelated exomesLink
Exome Aggregation Consortium61,486 unrelated exomesLink
Exome Aggregation Consortium61,486 unrelated exomesLink
Exome Aggregation Consortium61,486 unrelated exomesLink
Exome Aggregation Consortium61,486 unrelated exomesLink