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Paper Details

Mutant GNAS drives pancreatic tumourigenesis by inducing PKA-mediated SIK suppression and reprogramming lipid metabolism.
Nat Cell Biol
119
2018
GNAS, Gnas, GnasR201C, Gprotein s, IPMN, IPMNs, KRAS, KRAS mutations, Kras, Kras-, Kras-mutant pancreatic cancer cells, Kras-mutant pancreatic neoplasms, KrasG12D, Mutant Gnas, PDA, PDAs, PKA, SIK, Sik1-3, Siks, Tp53, cAMP, fatty acid, intraductal papillary mucinous neoplasms, mouse, pancreatic cancer, pancreatic ductal adenocarcinomas, pancreatic neoplasms, protein-kinase-A, salt, salt-inducible kinases, tumour
Author NameAffiliation
Krushna C PatraCenter for Cancer Research, Massachusetts General Hospital
Krushna C PatraHarvard Medical School
Daniel K NomuraUniversity of California berkeley
Wilhelm HaasCenter for Cancer Research, Massachusetts General Hospital
Nabeel BardeesyCenter for Cancer Research, Massachusetts General Hospital
Nabeel BardeesyHarvard Medical School
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