Skip to Main Content

Paper Details

Glioblastoma stem cells reprogram chromatin in vivo to generate selective therapeutic dependencies on DPY30 and phosphodiesterases.
Sci Transl Med
13
2022
DPY30, DPY30-expressing cells, Dpy-30 histone methyltransferase complex, GSC, GSCs, Glioblastoma, Glioblastoma stem cells, Glioblastomas, H3K4me3, Intracranial-specific genes, MLL, PDE, PDE4, PDE4B, PDX tumors, SET domain-containing 1, SET1, anticancer, cancers, cell culture, chromatin, cultured GSCs, glioblastoma, glioblastoma stem cells, histone H3 lysine, histone lysine methyltransferase, in vitro cultures, lysine, mice, mixed lineage leukemia, patient, phosphodiesterase, phosphodiesterases, rolipram, tumor, tumors
Author NameAffiliation
Briana C PragerUniversity of California
Briana C PragerCase Western Reserve University
Briana C PragerCleveland Clinic Lerner College of Medicine of Case Western Reserve University
Zhixin QiuUniversity of California
Zhixin QiuUniversity of Pittsburgh Medical Center Hillman Cancer Center
Robert J Wechsler-ReyaNCI-Designated Cancer Center, Sanford Burnham Prebys Medical Discovery Institute
Robert J Wechsler-ReyaNCI-Designated Cancer Center, Sanford Burnham Prebys Medical Discovery Institute
Jeremy N RichUniversity of California
Jeremy N RichUniversity of Pittsburgh Medical Center Hillman Cancer Center
Jeremy N RichUniversity of California
Jeremy N RichUniversity of Pittsburgh Medical Center Hillman Cancer Center
  • 1 - 11

Datasets

Release 1.2