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Paper Details

Production of Gene-Corrected Adult Beta Globin Protein in Human Erythrocytes Differentiated from Patient iPSCs After Genome Editing of the Sickle Point Mutation.
Stem Cells
137
2015
16-kDa -globin protein, Adult Beta Globin Protein, Cas9, Erythrocytes, HBB, HBB allele, HBB gene, Human, Human Erythrocytes, Human iPSCs, Human induced pluripotent stem cells, Patient, Patient iPSCs, SCD, SCD HBB gene, SCD allele, Sickle, TALENs, adult -globin proteins, differentiated erythrocytes, disease-free cells, donor DNA template, endogenous HBB locus, erythrocytes, gene-corrected cells, genome, genome-edited iPSCs, guide RNA, human, human iPSCs, iPSC clones, iPSC line, iPSCs, induced pluripotent stem cells, matured erythrocytes, parental, patient, patient-derived iPSCs, patients, reticulocytes, sickle cell disease, wild-type HBB DNA, zinc, zinc finger nucleases
Author NameAffiliation
Xiaosong HuangDepartment of Medicine Institute for Cell Engineering.
Xiaosong HuangDepartment of Medicine Institute for Cell Engineering.
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