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Paper Details

MEK Inhibition Synergizes with TYK2 Inhibitors in NF1-Associated Malignant Peripheral Nerve Sheath Tumors.
Clin Cancer Res
4
2023
ERK, MEK, MPNST, Malignant peripheral nerve sheath tumors, NF1, NF1-Associated Malignant Peripheral Nerve Sheath Tumors, NF1-assosciated MPNST, RNA, TYK2, deucravacitinib, human, mirdametinib, murine, murine and human MPNST cell lines, neurofibromatosis type 1 (NF1) cancer predisposition syndrome, pERK1/2, sarcomas
Author NameAffiliation
Xiaochun ZhangWashington University School of Medicine
Christine A PratilasSidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Kai PollardSidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Brigitte C WidemannCenter for Cancer Research
Angela C HirbeWashington University School of Medicine
Angela C HirbeSiteman Cancer Center, Washington University School of Medicine
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