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Paper Details

Targeted and genome-wide sequencing reveal single nucleotide variations impacting specificity of Cas9 in human stem cells.
Nat Commun
103
2014
-, CRISPR, Cas9, Cas9 nuclease, Cas9-modified hiPSC clones, Cas9-treated cells, SNV, Tafazzin gene, germline single-nucleotide variant, human, human genome, human stem cells, human-induced pluripotent stem cells, off-target site, off-target sites, treated cells
Author NameAffiliation
Luhan YangHarvard Medical School, USA [2] Wyss Institute for Biologically Inspired Engineering, Harvard University
Dennis GrishinHarvard Medical School
John AachHarvard Medical School
Raj ChariHarvard Medical School
Jian-Bing Fan
Jian-Bing Fan
Christine E SeidmanHarvard Medical School
Christine E SeidmanHarvard Medical School
Jonathan G SeidmanHarvard Medical School
Jonathan G SeidmanHarvard Medical School
William T PuBoston Children's Hospital
William T PuBoston Children's Hospital
George M ChurchHarvard Medical School, USA [2] Wyss Institute for Biologically Inspired Engineering, Harvard University
George M ChurchHarvard Medical School, USA [2] Wyss Institute for Biologically Inspired Engineering, Harvard University
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