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Paper Details

A flexible split prime editor using truncated reverse transcriptase improves dual-AAV delivery in mouse liver.
Molecular Therapy
31
2022
Cas9 split site, Cas9-which, Glu, Glu 573, PE, Pcsk9 gene, RNase H, RNase H domain, cPE573, cells, eRF1, mammalian cells, mouse, peptidyl release factor 1, reverse transcriptase, split, split prime editor, split sites, stop codon
Author NameAffiliation
Suet-Yan KwanRNA Therapeutics Institute, University of Massachusetts Medical School
Scot A WolfeUniversity of Massachusetts Medical School, USA Li Weibo Institute for Rare Diseases Research
Wen XueRNA Therapeutics Institute, University of Massachusetts Medical School, USA Li Weibo Institute for Rare Diseases Research
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Release 1.2