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Paper Details

Integrated allelic, transcriptional, and phenomic dissection of the cardiac effects of titin truncations in health and disease.
Sci Transl Med
319
2015
DCM, RNA, TTN, TTN exons, TTN gene, TTN isoform, TTN transcript, TTN-truncating variants, TTNtv, cardiodb, dilated cardiomyopathy, full-length titin, heart failure, human, patients, titin
Author NameAffiliation
Angharad M RobertsClinical Sciences Centre, Medical Research Council (MRC), Imperial College London, UK. National Institute for Health Research (NIHR) Cardiovascular Biomedical Research Unit at Royal Brompton & Harefield National Health Service (NHS) Foundation Trust and Imperial College London
Angharad M RobertsClinical Sciences Centre, Medical Research Council (MRC), Imperial College London, UK. National Institute for Health Research (NIHR) Cardiovascular Biomedical Research Unit at Royal Brompton & Harefield National Health Service (NHS) Foundation Trust and Imperial College London
James S WareNational Institute for Health Research (NIHR) Cardiovascular Biomedical Research Unit at Royal Brompton & Harefield National Health Service (NHS) Foundation Trust and Imperial College London, UK. National Heart & Lung Institute, Imperial College London, Harvard Medical School, USA. Broad Institute of Harvard and Massachusetts Institute of Technology
Daniel S HermanHarvard Medical School, USA. Broad Institute of Harvard and Massachusetts Institute of Technology, University of Washington
Daniel S HermanHarvard Medical School, USA. Broad Institute of Harvard and Massachusetts Institute of Technology, University of Washington
Sebastian SchaferMax Delbruck Center for Molecular Medicine
Arun John BaksiNational Institute for Health Research (NIHR) Cardiovascular Biomedical Research Unit at Royal Brompton & Harefield National Health Service (NHS) Foundation Trust and Imperial College London
Alexander G BickHarvard Medical School, USA. Broad Institute of Harvard and Massachusetts Institute of Technology
Rachel BuchanNational Institute for Health Research (NIHR) Cardiovascular Biomedical Research Unit at Royal Brompton & Harefield National Health Service (NHS) Foundation Trust and Imperial College London
Roddy WalshNational Institute for Health Research (NIHR) Cardiovascular Biomedical Research Unit at Royal Brompton & Harefield National Health Service (NHS) Foundation Trust and Imperial College London
Shibu JohnNational Institute for Health Research (NIHR) Cardiovascular Biomedical Research Unit at Royal Brompton & Harefield National Health Service (NHS) Foundation Trust and Imperial College London
Sam WilkinsonNational Institute for Health Research (NIHR) Cardiovascular Biomedical Research Unit at Royal Brompton & Harefield National Health Service (NHS) Foundation Trust and Imperial College London
Francesco MazzarottoNational Institute for Health Research (NIHR) Cardiovascular Biomedical Research Unit at Royal Brompton & Harefield National Health Service (NHS) Foundation Trust and Imperial College London, UK. National Heart & Lung Institute, Imperial College London
Leanne E FelkinNational Institute for Health Research (NIHR) Cardiovascular Biomedical Research Unit at Royal Brompton & Harefield National Health Service (NHS) Foundation Trust and Imperial College London, UK. National Heart & Lung Institute, Imperial College London
Sungsam GongNational Institute for Health Research (NIHR) Cardiovascular Biomedical Research Unit at Royal Brompton & Harefield National Health Service (NHS) Foundation Trust and Imperial College London
Jacqueline A L MacArthurEuropean Bioinformatics Institute
Fiona CunninghamEuropean Bioinformatics Institute
Fiona CunninghamEuropean Bioinformatics Institute
Jason FlannickBroad Institute of Harvard and Massachusetts Institute of Technology, Massachusetts General Hospital
Stacey GabrielBroad Institute of Harvard and Massachusetts Institute of Technology
Stacey GabrielBroad Institute of Harvard and Massachusetts Institute of Technology
David AltshulerBroad Institute of Harvard and Massachusetts Institute of Technology, USA. Center for Human Genetic Research, Massachusetts General Hospital
David AltshulerBroad Institute of Harvard and Massachusetts Institute of Technology, USA. Center for Human Genetic Research, Massachusetts General Hospital
Peter S MacdonaldSt Vincent's Hospital, Australia. Victor Chang Cardiac Research Institute, University of New South Wales
Matthias HeinigMax Delbruck Center for Molecular Medicine
Anne KeoghSt Vincent's Hospital, Australia. Victor Chang Cardiac Research Institute, University of New South Wales
Christopher S HaywardSt Vincent's Hospital, Australia. Victor Chang Cardiac Research Institute, University of New South Wales
Nicholas R BannerNational Heart & Lung Institute, Imperial College London, UK. Royal Brompton & Harefield NHS Foundation Trust, Harefield Hospital
Dudley J PennellNational Institute for Health Research (NIHR) Cardiovascular Biomedical Research Unit at Royal Brompton & Harefield National Health Service (NHS) Foundation Trust and Imperial College London, UK. National Heart & Lung Institute, Imperial College London
Declan P O'ReganClinical Sciences Centre, Medical Research Council (MRC), Imperial College London
Ru San Tan
Antonio de MarvaoClinical Sciences Centre, Medical Research Council (MRC), Imperial College London
Timothy J W DawesClinical Sciences Centre, Medical Research Council (MRC), Imperial College London
Ankur GulatiNational Institute for Health Research (NIHR) Cardiovascular Biomedical Research Unit at Royal Brompton & Harefield National Health Service (NHS) Foundation Trust and Imperial College London
Emma J BirksNational Heart & Lung Institute, Imperial College London, University of Louisville and Jewish Hospital
Magdi H YacoubNational Heart & Lung Institute, Imperial College London
Michael H RadkeMax Delbruck Center for Molecular Medicine
Michael GotthardtMax Delbruck Center for Molecular Medicine
James G WilsonUniversity of Mississippi Medical Center
James G WilsonUniversity of Mississippi Medical Center
Christopher J O'Donnelland Blood Institute's Framingham Heart Study, and Blood Institute
Christopher J O'Donnelland Blood Institute's Framingham Heart Study, and Blood Institute
Sanjay K PrasadNational Institute for Health Research (NIHR) Cardiovascular Biomedical Research Unit at Royal Brompton & Harefield National Health Service (NHS) Foundation Trust and Imperial College London
Paul J R BartonNational Institute for Health Research (NIHR) Cardiovascular Biomedical Research Unit at Royal Brompton & Harefield National Health Service (NHS) Foundation Trust and Imperial College London, UK. National Heart & Lung Institute, Imperial College London
Diane FatkinSt Vincent's Hospital, Australia. Victor Chang Cardiac Research Institute, University of New South Wales
Norbert H??bnerMax Delbruck Center for Molecular Medicine, Germany. Charite-Universitatsmedizin
Norbert H??bnerMax Delbruck Center for Molecular Medicine, Germany. Charite-Universitatsmedizin
Jonathan G SeidmanHarvard Medical School
Jonathan G SeidmanHarvard Medical School
Christine E SeidmanHarvard Medical School, USA. Broad Institute of Harvard and Massachusetts Institute of Technology, Brigham and Women's Hospital, USA. Howard Hughes Medical Institute
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