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Paper Details

CRISPR Editing of Mutant IDH1 R132H Induces a CpG Methylation-Low State in Patient-Derived Glioma Models of G-CIMP.
Molecular Cancer Research
15
2019
Cas9, CpG, CpG sites, CpG-island shores, D-2-hydroxyglutarate, D-2HG, DNA, G, G-, G-CIMP sites, G-CIMP-, G-CIMP-defining CpG sites, G-CIMP-low-like phenotype, Glioma, IDH, IDH alleles, IDH1, IDH1 R132H, IDH1 alleles, IDH1 mutation, IDH1/2, IDH1/2 mutations, IDH1R132H, Mutant IDH1 R132H, Patient, Patient-Derived Glioma Models, R132H, World, glioblastomas, glioma, island, isocitrate, isocitrate dehydrogenases 1 and 2, malignant glioma, malignant glioma cells, mutant allele, open, patient, patient-derived IDH1R132H/WT glioma cell lines, transcription start sites, tumor, tumor samples
Author NameAffiliation
Yiping HeDuke University
Yiping HeDuke University Medical Center
Hai YanDuke University
Hai YanDuke University Medical Center
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