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Paper Details

Subependymal giant cell astrocytomas are characterized by mTORC1 hyperactivation, a very low somatic mutation rate, and a unique gene expression profile.
Mod Pathol
12
2021
Cancer, EOMES, HMX2, HMX3, IRF6, SEGA, SEGA-specific TFs, SEGAs, SIX3, Subependymal, Subependymal giant cell astrocytomas, Subependymal giant-cell astrocytomas, TSC, TSC1, TSC2, Tuberous Sclerosis, VAX1, brain tumors, chr16p, chr9q, differentially expressed genes, ganglioglioma, gene, glioblastoma, homeobox transcription factors, low grade diffuse gliomas, mTORC1, neuroepithelial, neuroepithelial cell, neurologic symptoms, patients, tumor
Author NameAffiliation
Jaegil KimBroad Institute of MIT and Harvard
Joel S ParkerLineberger Comprehensive Cancer Center, The University of North Carolina at Chapel Hill
Joel S ParkerLineberger Comprehensive Cancer Center, The University of North Carolina at Chapel Hill
Len TaingCenter for Functional Cancer Epigenetics, Dana-Farber Cancer Institute and Harvard Medical School
Sanda AlexandrescuBoston Children's Hospital, Harvard Medical School
Hart G W LidovBoston Children's Hospital, Harvard Medical School
Gad GetzBroad Institute of MIT and Harvard
Gad GetzBroad Institute of MIT and Harvard
Orrin DevinskyNew York University School of Medicine
Michael S LawrenceBroad Institute of MIT and Harvard, Massachusetts General Hospital Cancer Center, Harvard Medical School
Keith L LigonDana-Farber Cancer Institute
David W EllisonSt. Jude Children's Research Hospital
Mustafa SahinBoston Children's Hospital, Harvard Medical School
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