-Weber syndrome, AEB071, ANGPT2, Angiopoietin-2, CM, CONCLUSIONS Gq-R183Q, Capillary malformation, DSCR, DSCR1, Down syndrome, Down syndrome critical region protein, EC, EC-, EC-R183Q, EC-WT, ECs, Endothelial, Endothelial GNAQ, Enlarged, G-protein q subunit, GNAQ, Gq, NF-B, PKC, PLC (, PLC3, R183Q, Sturge, Sturge-Weber syndrome, YM-254890, angiopoietin-2, brain CM, c.548G, c.548G>A, calcineurin, endothelial Gq-R183Q, endothelial cells, human, mRNA, mice, mutant, mutant Gq, mutant versus, normal human endothelial colony forming cells, nuclear factor kappa B, p.R183Q, phospholipase C), proangiogenic, protein kinase C, shRNA, wild-type EC, wild-type GNAQ