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Paper Details

PI3Kγ inhibition suppresses microglia/TAM accumulation in glioblastoma microenvironment to promote exceptional temozolomide response.
Proc Natl Acad Sci U S A
40
2021
/, Glioblastoma, Glioblastoma-associated microglia, IL11, MYC, PI3K, RNA profiles, STAT3, TAM, TMZ, glioblastoma, glioblastoma cells, interleukin 11, macrophage, macrophages, microglia, murine, murine glioblastoma models, myeloid cell, neoplastic, phosphoinositide-3-kinase, phosphoinositide-3-kinase gamma isoform, stem cell states, temozolomide, tumor
Author NameAffiliation
Frank B FurnariLudwig Institute for Cancer Research, University of California San Diego
Jeremy N RichUniversity of California San Diego
Jeremy N RichUniversity of California San Diego
Christopher K GlassUniversity of California San Diego
Christopher K GlassUniversity of California San Diego
Clark C ChenUniversity of Minnesota
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