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Paper Details

Discovery of Potent and Selective WDR5 Proteolysis Targeting Chimeras as Potential Therapeutics for Pancreatic Cancer.
J Med Chem
3
2023
CRBN, CRBN neo-, IKZF1, MS132, PDAC, PDAC cells, Pancreatic Cancer, VHL, WDR5, cereblon, mice, pancreatic, pancreatic cancer, pancreatic ductal adenocarcinoma, pancreatic ductal adenocarcinoma (PDAC) cells, von Hippel-Lindau
Author NameAffiliation
Laura E HerringUniversity of North Carolina at Chapel Hill School of Medicine
Ling XieUniversity of North Carolina at Chapel Hill
Jian JinMount Sinai Center for Therapeutics Discovery, Icahn School of Medicine at Mount Sinai
Jian JinDepartments of Pharmacological Sciences and Oncological Sciences, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai
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Datasets

Release 1.2