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Paper Details

Targeting immunosuppressive macrophages overcomes PARP inhibitor resistance in BRCA1-associated triple-negative breast cancer.
Nat Cancer
114
2021
BRCA, BRCA-associated TNBC, BRCA-associated triple-negative breast cancer, BRCA-deficient tumors, BRCA1, BRCA1-associated triple-negative breast cancer, CD8+, CD8+ T-cells, CSF-1R, PARP, SREBP-1, TNBC, glucose, human, immunosuppressive macrophages, infiltrating immune cell type, macrophage, macrophages, patients, sterol, sterol regulatory element-binding protein 1, tumor
Author NameAffiliation
Jia-Ren LinHarvard Medical School
William M OldhamBrigham and Women's Hospital and Harvard Medical School
Sandro SantagataHarvard Medical School
Sandro SantagataLudwig Center for Cancer Research at Harvard, Harvard Medical School
Sandro SantagataBrigham and Women's Hospital, Harvard Medical School
Judy E GarberDana-Farber Cancer Institute and Department of Medicine, Harvard Medical School
Peter K SorgerHarvard Medical School
Peter K SorgerLudwig Center for Cancer Research at Harvard, Harvard Medical School
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