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Paper Details

Cyclic multiplex fluorescent immunohistochemistry and machine learning reveal distinct states of astrocytes and microglia in normal aging and Alzheimer's disease.
J Neuroinflammation
13
2022
6226, AD, ALDH1L1, ALDH1L1+, Alzheimer's disease, Astrocytes, CD68, EAAT1, EAAT2, GFAP, GS, IBA1, Intermediate astrocytes, MHC2, TMEM119, TSPO, YKL-40, astrocytes, astrocytic, astroglial, ferritin, glial, glial cells, human, intermediate astrocytes, intermediate microglia, microglia, microglial, microglial profiles, neurodegeneration, neurofibrillary tangles, neuronal, phospho-tau, reactive astrocytes, reactive microglia, single, transitional or "resilient" glia, vimentin
Author NameAffiliation
Matthew P FroschMassachusetts General Hospital
Matthew P FroschHarvard Medical School
Matthew P FroschMassachusetts Alzheimer's Disease Research Center
Matthew P FroschMassGeneral Institute for Neurodegenerative Disease
Matthew P FroschMassachusetts General Hospital
Matthew P FroschMassGeneral Institute for Neurodegenerative Disease
Matthew P FroschMassachusetts Alzheimer's Disease Research Center
Matthew P FroschHarvard Medical School
Sudeshna DasMassachusetts General Hospital
Sudeshna DasHarvard Medical School
Sudeshna DasMassachusetts Alzheimer's Disease Research Center
Sudeshna DasMassGeneral Institute for Neurodegenerative Disease
Sudeshna DasMassachusetts General Hospital
Sudeshna DasMassGeneral Institute for Neurodegenerative Disease
Sudeshna DasMassachusetts Alzheimer's Disease Research Center
Sudeshna DasHarvard Medical School
Bradley T HymanMassachusetts General Hospital
Bradley T HymanMassGeneral Institute for Neurodegenerative Disease
Bradley T HymanMassachusetts Alzheimer's Disease Research Center
Bradley T HymanHarvard Medical School
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