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Paper Details

Targeted RNA editing in brainstem alleviates respiratory dysfunction in a mouse model of Rett syndrome.
Proc Natl Acad Sci U S A
10
2022
Editase, MECP2, MECP2 protein, MeCP2, MeCP2 protein, Methyl, Methyl CpG binding protein 2, RNA, Rett, Rett syndrome, adenosine, bioengineered wild-type ADAR2 catalytic domain, endogenous MECP2, guanosine, guide RNA, human, humans, mice, mouse, neurological disease, patient, respiratory dysfunction
Animals, Brain Stem, Disease Models, Animal, Humans, Male, Methyl-CpG-Binding Protein 2, Mice, Mutation, RNA Editing, Respiration Disorders, Rett Syndrome
Author NameAffiliation
John R SinnamonVollum Institute, Oregon Health and Science University
Michael E JacobsonVollum Institute, Oregon Health and Science University
John F YungVollum Institute, Oregon Health and Science University
Jenna R FiskVollum Institute, Oregon Health and Science University
Sophia JengKnight Cancer Institute, Oregon Health and Science University
Shannon K McWeeneyKnight Cancer Institute, Oregon Health and Science University
Shannon K McWeeneyOregon Health and Science University
Shannon K McWeeneyDepartment of Medical Informatics and Clinical Epidemiology, Oregon Health and Science University
Shannon K McWeeneyOregon Clinical and Translational Research Institute, Oregon Health and Science University
Lindsay K ParmeleeOregon National Primate Research Center
Chi N ChanOregon National Primate Research Center
Siu-Pok YeeUniversity of Connecticut Health Center
Gail MandelVollum Institute, Oregon Health and Science University
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