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Paper Details

Enhanced homology-directed repair for highly efficient gene editing in hematopoietic stem/progenitor cells.
Blood
44
2021
+ cells, 53BP1, CD34+, CD34+ cells, CD34+ hematopoietic cells, Streptococcus pyogenes, Streptococcus pyogenes Cas9 mRNA, X, X-CGD, X-linked chronic granulomatous disease, exogenous promoters, gp91phox, gp91phox+ cells, hematopoietic stem/progenitor cells, oligodeoxynucleotide, p53-binding protein 1, quiescent, transduced cells
Author NameAffiliation
Sandra BurkettCenter for Cancer Research, National Cancer Institute, National Institutes of Health
Sandra BurkettCenter for Cancer Research, National Cancer Institute, National Institutes of Health
Benjamin P KleinstiverCenter for Genomic Medicine and Department of Pathology, Massachusetts General Hospital
Benjamin P KleinstiverHarvard Medical School
Matthew H PorteusStanford University
Douglas B KuhnsLaboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health
Xiaolin WuLeidos Biomedical Research Inc.
Xiaolin WuLeidos Biomedical Research Inc.
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Release 1.2