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Paper Details

Engineered Bcor mutations lead to acute leukemia of progenitor B-1 lymphocyte origin in a sensitized background.
Blood
9
2019
9-bp "hotspot, B-1 lymphocyte progenitor origin, B-cell precursor ALL, BCL6 interacting corepressor, BCL6 interacting corepressor (Bcor) gene, Bcor, Bcor exon 8, Bcor mutations, Bcor sgRNA, Bcor sgRNAs, Bcor small guide RNAs, Igh gene, JAK, Jak kinase genes, NP23, NP23 hematopoietic stem and progenitor cells, NUP98, PHF23, acute leukemia, acute lymphoblastic leukemia, fetal liver cells, hematopoietic stem and progenitor cells, human, human B-cell precursor, mice, murine, murine pro-B1 ALL, pro, pro-, pro-B1, pro-B1 ALL, pro-B1 ALL cell lines, progenitor B-1 lymphocyte origin, progenitor immunophenotype, ruxolitinib, short palindromic repeats, tofacitinib
Author NameAffiliation
Robert Coleman LindsleyBrigham and Women's Hospital
Robert Coleman LindsleyDana-Farber Cancer Institute, Harvard Medical School
Robert L WalkerCenter for Cancer Research, National Cancer Institute, National Institutes of Health
Robert L WalkerCenter for Cancer Research, National Cancer Institute, National Institutes of Health
Yuelin J ZhuCenter for Cancer Research, National Cancer Institute, National Institutes of Health
Yuelin J ZhuCenter for Cancer Research, National Cancer Institute, National Institutes of Health
Benjamin L EbertBrigham and Women's Hospital
Benjamin L EbertDana-Farber Cancer Institute, Harvard Medical School
Paul S MeltzerCenter for Cancer Research, National Cancer Institute, National Institutes of Health
Paul S MeltzerCenter for Cancer Research, National Cancer Institute, National Institutes of Health
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