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Paper Details

Tranexamic Acid in Patients Undergoing Noncardiac Surgery.
N Engl J Med
98
2022
POISE, Patients, Tranexamic Acid, Tranexamic acid, hypertension, hypotension, myocardial injury, nonhemorrhagic stroke, patients, peripheral arterial thrombosis, proximal, tranexamic acid, venous thromboembolism
Author NameAffiliation
Amit X GargFrom the Population Health Research Institute (P.J.D., McMaster University, Western University, Queen's University and Kingston Health Sciences Centre, Centre Hospitalier de l'Universite de Montreal (E.D.), Jewish General Hospital, McGill University (T.C.), University of Saskatchewan, University of Adelaide (T.W.P.), Royal Adelaide Hospital (T.W.P.), Monash University (T.R.), Melbourne Medical School, University of Melbourne (K.L.), E. Meshalkin National Medical Research Center (V.L.), V. Zelman Institute of Medicine and Psychology (S.V.A.), Novosibirsk State University, Saint Petersburg State University Hospital, and V. Negovsky Reanimatology Research Institute, First Moscow State Medical University (Sechenov University), A.T.) and the Anesthesiology Institute (D.I.S., Cleveland Clinic, Cleveland Chinese University of Hong Kong, Public Health and Clinical Epidemiology Service, Institut d'Investigacio Biomedica Sant Pau, Hospital Vall d'Hebron, Universitat Autonoma de Barcelona (M.N.), Santa Creu i Sant Pau University Hospital (P.P.), Hospital Clinico Universitario de Valladolid, University of Malaya, Malaysia (C.Y.W.) St. John's Medical College, Surat Institute of Digestive Sciences Hospital and Research Center, IRCCS San Raffaele Scientific Institute, Vita Salute San Raffaele University, the Netherlands (Y.V.K.) Jagiellonian University Medical College, Center for Intensive Care and Perioperative Medicine, Poland (W.S.) Centre Hospitalier Universitaire Brugmann, Universite Libre de Bruxelles, Auckland City Hospital, University of Auckland, University Hospital Bonn, Copenhagen University Hospital-Bispebjerg and Frederiksberg, University of Copenhagen, Copenhagen (C.S.M.) Shifa International Hospital, Universidad de Los Andes, Clinica Santa Maria, Medical University of Vienna, Vienna (E.F.) Universidade Federal do Rio Grande do Sul, Hospital de Clinicas de Porto Alegre, National Institute for Health Technology Assessment, and Hospital Moinhos de Vento, Hospital Paris Saint Joseph, University of Paris
Salim YusufFrom the Population Health Research Institute (P.J.D., McMaster University, Western University, Queen's University and Kingston Health Sciences Centre, Centre Hospitalier de l'Universite de Montreal (E.D.), Jewish General Hospital, McGill University (T.C.), University of Saskatchewan, University of Adelaide (T.W.P.), Royal Adelaide Hospital (T.W.P.), Monash University (T.R.), Melbourne Medical School, University of Melbourne (K.L.), E. Meshalkin National Medical Research Center (V.L.), V. Zelman Institute of Medicine and Psychology (S.V.A.), Novosibirsk State University, Saint Petersburg State University Hospital, and V. Negovsky Reanimatology Research Institute, First Moscow State Medical University (Sechenov University), A.T.) and the Anesthesiology Institute (D.I.S., Cleveland Clinic, Cleveland Chinese University of Hong Kong, Public Health and Clinical Epidemiology Service, Institut d'Investigacio Biomedica Sant Pau, Hospital Vall d'Hebron, Universitat Autonoma de Barcelona (M.N.), Santa Creu i Sant Pau University Hospital (P.P.), Hospital Clinico Universitario de Valladolid, University of Malaya, Malaysia (C.Y.W.) St. John's Medical College, Surat Institute of Digestive Sciences Hospital and Research Center, IRCCS San Raffaele Scientific Institute, Vita Salute San Raffaele University, the Netherlands (Y.V.K.) Jagiellonian University Medical College, Center for Intensive Care and Perioperative Medicine, Poland (W.S.) Centre Hospitalier Universitaire Brugmann, Universite Libre de Bruxelles, Auckland City Hospital, University of Auckland, University Hospital Bonn, Copenhagen University Hospital-Bispebjerg and Frederiksberg, University of Copenhagen, Copenhagen (C.S.M.) Shifa International Hospital, Universidad de Los Andes, Clinica Santa Maria, Medical University of Vienna, Vienna (E.F.) Universidade Federal do Rio Grande do Sul, Hospital de Clinicas de Porto Alegre, National Institute for Health Technology Assessment, and Hospital Moinhos de Vento, Hospital Paris Saint Joseph, University of Paris
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ClinicalTrials.govClinicalTrials.gov, a registry and results database of of privately and publicly funded clinical studies conducted around the world, is operated by the U.S. National Library of Medicine (NLM). Structured study information is provided, voluntarily or to meet legal and policy requirements, by the sponsor or investigator responsible for the research. NLM does not verify the scientific validity or relevance of the submitted information beyond a limited quality control review for apparent errors, deficiencies, or inconsistencies.Link
ClinicalTrials.govClinicalTrials.gov, a registry and results database of of privately and publicly funded clinical studies conducted around the world, is operated by the U.S. National Library of Medicine (NLM). Structured study information is provided, voluntarily or to meet legal and policy requirements, by the sponsor or investigator responsible for the research. NLM does not verify the scientific validity or relevance of the submitted information beyond a limited quality control review for apparent errors, deficiencies, or inconsistencies.Link
ClinicalTrials.govClinicalTrials.gov, a registry and results database of of privately and publicly funded clinical studies conducted around the world, is operated by the U.S. National Library of Medicine (NLM). Structured study information is provided, voluntarily or to meet legal and policy requirements, by the sponsor or investigator responsible for the research. NLM does not verify the scientific validity or relevance of the submitted information beyond a limited quality control review for apparent errors, deficiencies, or inconsistencies.Link
ClinicalTrials.govClinicalTrials.gov, a registry and results database of of privately and publicly funded clinical studies conducted around the world, is operated by the U.S. National Library of Medicine (NLM). Structured study information is provided, voluntarily or to meet legal and policy requirements, by the sponsor or investigator responsible for the research. NLM does not verify the scientific validity or relevance of the submitted information beyond a limited quality control review for apparent errors, deficiencies, or inconsistencies.Link
ClinicalTrials.govClinicalTrials.gov, a registry and results database of of privately and publicly funded clinical studies conducted around the world, is operated by the U.S. National Library of Medicine (NLM). Structured study information is provided, voluntarily or to meet legal and policy requirements, by the sponsor or investigator responsible for the research. NLM does not verify the scientific validity or relevance of the submitted information beyond a limited quality control review for apparent errors, deficiencies, or inconsistencies.Link
ClinicalTrials.govClinicalTrials.gov, a registry and results database of of privately and publicly funded clinical studies conducted around the world, is operated by the U.S. National Library of Medicine (NLM). Structured study information is provided, voluntarily or to meet legal and policy requirements, by the sponsor or investigator responsible for the research. NLM does not verify the scientific validity or relevance of the submitted information beyond a limited quality control review for apparent errors, deficiencies, or inconsistencies.Link
ClinicalTrials.govClinicalTrials.gov, a registry and results database of of privately and publicly funded clinical studies conducted around the world, is operated by the U.S. National Library of Medicine (NLM). Structured study information is provided, voluntarily or to meet legal and policy requirements, by the sponsor or investigator responsible for the research. NLM does not verify the scientific validity or relevance of the submitted information beyond a limited quality control review for apparent errors, deficiencies, or inconsistencies.Link
ClinicalTrials.govClinicalTrials.gov, a registry and results database of of privately and publicly funded clinical studies conducted around the world, is operated by the U.S. National Library of Medicine (NLM). Structured study information is provided, voluntarily or to meet legal and policy requirements, by the sponsor or investigator responsible for the research. NLM does not verify the scientific validity or relevance of the submitted information beyond a limited quality control review for apparent errors, deficiencies, or inconsistencies.Link
ClinicalTrials.govClinicalTrials.gov, a registry and results database of of privately and publicly funded clinical studies conducted around the world, is operated by the U.S. National Library of Medicine (NLM). Structured study information is provided, voluntarily or to meet legal and policy requirements, by the sponsor or investigator responsible for the research. NLM does not verify the scientific validity or relevance of the submitted information beyond a limited quality control review for apparent errors, deficiencies, or inconsistencies.Link
ClinicalTrials.govClinicalTrials.gov, a registry and results database of of privately and publicly funded clinical studies conducted around the world, is operated by the U.S. National Library of Medicine (NLM). Structured study information is provided, voluntarily or to meet legal and policy requirements, by the sponsor or investigator responsible for the research. NLM does not verify the scientific validity or relevance of the submitted information beyond a limited quality control review for apparent errors, deficiencies, or inconsistencies.Link
ClinicalTrials.govClinicalTrials.gov, a registry and results database of of privately and publicly funded clinical studies conducted around the world, is operated by the U.S. National Library of Medicine (NLM). Structured study information is provided, voluntarily or to meet legal and policy requirements, by the sponsor or investigator responsible for the research. NLM does not verify the scientific validity or relevance of the submitted information beyond a limited quality control review for apparent errors, deficiencies, or inconsistencies.Link
ClinicalTrials.govClinicalTrials.gov, a registry and results database of of privately and publicly funded clinical studies conducted around the world, is operated by the U.S. National Library of Medicine (NLM). Structured study information is provided, voluntarily or to meet legal and policy requirements, by the sponsor or investigator responsible for the research. NLM does not verify the scientific validity or relevance of the submitted information beyond a limited quality control review for apparent errors, deficiencies, or inconsistencies.Link
ClinicalTrials.govClinicalTrials.gov, a registry and results database of of privately and publicly funded clinical studies conducted around the world, is operated by the U.S. National Library of Medicine (NLM). Structured study information is provided, voluntarily or to meet legal and policy requirements, by the sponsor or investigator responsible for the research. NLM does not verify the scientific validity or relevance of the submitted information beyond a limited quality control review for apparent errors, deficiencies, or inconsistencies.Link
ClinicalTrials.govClinicalTrials.gov, a registry and results database of of privately and publicly funded clinical studies conducted around the world, is operated by the U.S. National Library of Medicine (NLM). Structured study information is provided, voluntarily or to meet legal and policy requirements, by the sponsor or investigator responsible for the research. NLM does not verify the scientific validity or relevance of the submitted information beyond a limited quality control review for apparent errors, deficiencies, or inconsistencies.Link
ClinicalTrials.govClinicalTrials.gov, a registry and results database of of privately and publicly funded clinical studies conducted around the world, is operated by the U.S. National Library of Medicine (NLM). Structured study information is provided, voluntarily or to meet legal and policy requirements, by the sponsor or investigator responsible for the research. NLM does not verify the scientific validity or relevance of the submitted information beyond a limited quality control review for apparent errors, deficiencies, or inconsistencies.Link
Release 1.2