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Paper Details

Tumor-intrinsic PRC2 inactivation drives a context-dependent immune-desert microenvironment and is sensitized by immunogenic viruses.
J Clin Invest
9
2022
EED, IFN-, MPNSTs, MVA, PRC2, PRC2-, PRC2-loss tumors, SUZ12, T cell infiltrates, TME, Tumor, cancer, cancers, chromatin landscape, embryonic ectoderm development, immune-, malignant peripheral nerve sheath tumors, modified vaccinia virus Ankara, polycomb-repressive complex 2, suppressor, suppressor of zeste 12 homolog, tumor, tumor cell, tumor immune infiltrates, tumors, zeste 12
Author NameAffiliation
Richard KocheCenter for Epigenetics Research, MSK Cancer Center
Richard KocheCenter for Epigenetics Research, MSK Cancer Center
Deyou ZhengAlbert Einstein College of Medicine
Deyou Zheng
Deyou ZhengAlbert Einstein College of Medicine
Cristina R AntonescuMSK Cancer Center
Cristina R AntonescuMSK Cancer Center
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