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Paper Details

Therapeutic implications of activating noncanonical PIK3CA mutations in head and neck squamous cell carcinoma.
J Clin Invest
22
2021
Alpelisib, HNSCC, PI3K, PIK3CA, PIK3CA mutation, PIK3CA mutations, Q75E, alpelisib, breast cancers, canonical hotspots, cellular models, head and neck squamous cell carcinoma, p110 catalytic subunit, patient, patients, tumors, xenograft
Animals, Class I Phosphatidylinositol 3-Kinases, Head and Neck Neoplasms, Humans, Male, Mice, Middle Aged, Mutation, Protein Domains, Squamous Cell Carcinoma of Head and Neck, Thiazoles
Author NameAffiliation
Nan JinUniversity of California San Francisco
Bhumsuk KeamSeoul National University Hospital
Ja Young ChoUniversity of California San Francisco
Michelle LeeUniversity of California San Francisco
Hye Ryun KimYonsei University College of Medicine, Yonsei Cancer Center
Hayarpi TorosyanCardiovascular Research Institute and.
Natalia JuraCardiovascular Research Institute and.
Natalia JuraUniversity of California San Francisco
Patrick Kwok-Shing NgInstitute for Personalized Cancer Therapy, The University of Texas MD Anderson Cancer Center
Patrick Kwok-Shing Ng
Gordon B MillsKnight Cancer Institute, Oregon Health & Science University
Gordon B MillsKnight Cancer Institute, Oregon Health & Science University
Hua LiUniversity of California San Francisco
Yan ZengUniversity of California San Francisco
Zohar Barbash
Gabi Tarcic
Hyunseok KangUniversity of California San Francisco
Julie E BaumanUniversity of Arizona
Mi-Ok Kim
Nathan K VanLandinghamUniversity of California San Francisco
Danielle L SwaneyUniversity of California San Francisco
Danielle L SwaneyQuantitative Biosciences Institute (QBI), University of California San Francisco
Danielle L SwaneyJ. David Gladstone Institutes
Nevan J Krogan (CM4AI)University of California San Francisco
Nevan J Krogan (CM4AI)Quantitative Biosciences Institute (QBI), University of California San Francisco
Nevan J Krogan (CM4AI)J. David Gladstone Institutes
Daniel E JohnsonUniversity of California San Francisco
Jennifer R GrandisUniversity of California San Francisco
Jennifer R GrandisUniversity of California San Francisco
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