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Paper Details

Inhibition of Dihydroorotate Dehydrogenase Overcomes Differentiation Blockade in Acute Myeloid Leukemia.
Cell
305
2016
AML, Acute Myeloid Leukemia, DHODH, Dihydroorotate, Dihydroorotate Dehydrogenase, HoxA9, HoxA9 model system, acute myeloid leukemia, dihydroorotate, dihydroorotate dehydrogenase, human, human and mouse AML models, leukemia, leukemia-initiating cells, leukemic, leukemic myeloblasts, mouse
Author NameAffiliation
Timothy A LewisCenter for the Science of Therapeutics, Broad Institute
Anna WallerCenter for Molecular Discovery, University of New Mexico
Larry A SklarCenter for Molecular Discovery, University of New Mexico
Clary B ClishBroad Institute
Clary B ClishBroad Institute
Paul A ClemonsCenter for the Science of Therapeutics, Broad Institute
Paul A ClemonsCenter for the Science of Therapeutics, Broad Institute
Stuart L SchreiberCenter for the Science of Therapeutics, Broad Institute, Harvard University, USA Howard Hughes Medical Institute
Stuart L SchreiberCenter for the Science of Therapeutics, Broad Institute, Harvard University, USA Howard Hughes Medical Institute
David T ScaddenCenter for Regenerative Medicine, Massachusetts General Hospital, USA Cancer Center, Harvard University, USA Harvard Stem Cell Institute
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