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Paper Details

The glutamine antagonist prodrug JHU-083 slows malignant glioma growth and disrupts mTOR signaling.
Neuro-Oncology Advances
22
2021
Cyclin D1 protein, GLS, GLS gene, Glutaminase, Glutaminase (GLS) gene silenced glioma cells, Glutamine, IDH1, IDH1 mut, IDH1 mut glioma, IDH1R132H, IDH1R132H isogenic cells, IDH2, IDHmut, IDHmut glioma, IDHmut glioma cell, Isocitrate, Isocitrate Dehydrogenase 1/2, JHU-083, TSC2, cancer, cancer cell, cancer cell lines, glioblastoma, glioma, glioma cell, glioma cells, glioma grade II and III, glutamine, guanine, isogenic cells, mTOR, malignant glioma, pS6 protein
Author NameAffiliation
Gregory J RigginsJohns Hopkins University School of Medicine
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