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Paper Details

Large-scale transcriptomic analysis reveals that pridopidine reverses aberrant gene expression and activates neuroprotective pathways in the YAC128 HD mouse.
Mol Neurodegener
24
2018
BDNF, D1R, GR, HD, Huntington Disease, NE-100, Pridopidine, RNAseq, YAC128, alternative exon, autosomal dominant neurodegenerative disorder, brain-derived neurotrophic factor, cAMP, calcium, dopamine, dopamine D1 receptor, genes, glucocorticoid receptor, human, human mHtt gene, mHtt, mice, mouse, mutant huntingtin protein, neuronal cultures, patients, pridopidine, rat, sigma-1 receptor, transcript
Author NameAffiliation
Rebecca KuskoImmuneering Corporation
Renan Escalante-ChongImmuneering Corporation
Liang Juin Tan
Michael R HaydenTeva Pharmaceutical Industries Ltd
Michael R Hayden
Michael R HaydenChild and Family Research Institute, University of British Columbia
Michael R HaydenYong Loo Lin School of Medicine, National University of Singapore
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