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Paper Details

Unveiling the Role of the Most Impactful Cardiovascular Risk Locus through Haplotype Editing.
Cell
83
2018
60 kb risk haplotype, 9p21, ANRIL, CAD, CAD risk genes, Cardiovascular Risk Locus, VSMC, VSMCs, cardiovascular disease, coding genes, coronary artery disease, haplotype-edited iPSCs, human, human genome, iPSCs, induced pluripotent stem cells, non-
Aged, Aged, 80 and over, Chromosomes, Human, Pair 9, Coronary Artery Disease, Female, Gene Editing, HEK293 Cells, Haplotypes, Humans, Induced Pluripotent Stem Cells, Leukocytes, Mononuclear, Male, Middle Aged, Muscle, Smooth, Vascular, Myocytes, Smooth Muscle, Polymorphism, Single Nucleotide, RNA, Long Noncoding, Transcription, Genetic
Author NameAffiliation
Valentina Lo SardoThe Scripps Research Institute
Pavel ChubukovThe Scripps Research Institute
William C FergusonThe Scripps Research Institute
Aditya KumarUniversity of California San Diego
Evan L TengUniversity of California San Diego
Michael DuranThe Scripps Research Institute
Lei ZhangInc.
Gregory J CostInc.
Adam J EnglerUniversity of California San Diego
Fyodor D UrnovInc.
Eric J TopolScripps Research Translational Institute, The Scripps Research Institute
Ali TorkamaniScripps Research Translational Institute, The Scripps Research Institute
Kristin K BaldwinThe Scripps Research Institute
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