Skip to Main Content

Paper Details

SARS-CoV-2 Orf6 hijacks Nup98 to block STAT nuclear import and antagonize interferon signaling.
Proc Natl Acad Sci U S A
352
2020
C, COVID-19, IFN, ISGs, Nup98, Orf6, Rae1, SARS, SARS-CoV, SARS-CoV-2, SARS-CoV-2 Orf6, STAT, STAT1, STAT2, Severe acute respiratory syndrome coronavirus, anti-IFN, arginine, coronavirus disease 2019, importin, interferon, karyopherin, methionine, methionine-to-arginine substitution at residue 58
Active Transport, Cell Nucleus, Animals, Binding Sites, COVID-19, Chlorocebus aethiops, HEK293 Cells, Humans, Interferons, Nuclear Matrix-Associated Proteins, Nuclear Pore, Nuclear Pore Complex Proteins, Nucleocytoplasmic Transport Proteins, Protein Binding, STAT1 Transcription Factor, STAT2 Transcription Factor, Signal Transduction, Vero Cells, Viral Proteins
Author NameAffiliation
Lisa MiorinIcahn School of Medicine at Mount Sinai
Lisa MiorinGlobal Health Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai
Thomas KehrerIcahn School of Medicine at Mount Sinai
Thomas KehrerGlobal Health Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai
Maria Teresa S??nchez-AparicioIcahn School of Medicine at Mount Sinai
Maria Teresa S??nchez-AparicioGlobal Health Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai
Ke ZhangUniversity of Texas Southwestern Medical Center
Phillip CohenIcahn School of Medicine at Mount Sinai
Roosheel S PatelIcahn School of Medicine at Mount Sinai
Anastasija CupicIcahn School of Medicine at Mount Sinai
Anastasija CupicGlobal Health Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai
Tadashi MakioUniversity of Alberta
Menghan MeiVanderbilt University School of Medicine
Elena MorenoIcahn School of Medicine at Mount Sinai
Elena MorenoGlobal Health Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai
Oded DanzigerIcahn School of Medicine at Mount Sinai
Kris M WhiteIcahn School of Medicine at Mount Sinai
Kris M WhiteGlobal Health Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai
Raveen RathnasingheIcahn School of Medicine at Mount Sinai
Raveen RathnasingheGlobal Health Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai
Melissa B UccelliniIcahn School of Medicine at Mount Sinai
Melissa B UccelliniGlobal Health Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai
Shengyan GaoUniversity of Texas Southwestern Medical Center
Teresa AydilloIcahn School of Medicine at Mount Sinai
Teresa AydilloGlobal Health Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai
Ignacio MenaIcahn School of Medicine at Mount Sinai
Ignacio MenaGlobal Health Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai
Xin YinSanford Burnham Prebys Medical Discovery Institute
Laura Martin-SanchoSanford Burnham Prebys Medical Discovery Institute
Nevan J Krogan (CM4AI)Icahn School of Medicine at Mount Sinai
Nevan J Krogan (CM4AI)Quantitative Biosciences Institute, University of California San Francisco
Nevan J Krogan (CM4AI)Gladstone Institute of Data Science and Biosciences, J. David Gladstone Institutes
Nevan J Krogan (CM4AI)University of California San Francisco
Sumit K ChandaSanford Burnham Prebys Medical Discovery Institute
Michael SchotsaertIcahn School of Medicine at Mount Sinai
Michael SchotsaertGlobal Health Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai
Richard W WozniakUniversity of Alberta
Yi RenVanderbilt University School of Medicine
Brad R RosenbergIcahn School of Medicine at Mount Sinai
Beatriz M A FontouraUniversity of Texas Southwestern Medical Center
Adolfo Garc??a-SastreIcahn School of Medicine at Mount Sinai
Adolfo Garc??a-SastreGlobal Health Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai
Adolfo Garc??a-SastreIcahn School of Medicine at Mount Sinai
Adolfo Garc??a-SastreTisch Cancer Institute, Icahn School of Medicine at Mount Sinai
  • 1 - 44

Datasets

Release 1.2