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Paper Title
Immediate utility of two approved agents to target both the metabolic mevalonate pathway and its restorative feedback loop.
PubMed
Paper Journal Title
Cancer Res
Paper Citation Count
61
Paper Publication Year
2014
Bio Mention
AML, Dipyridamole, HMG-CoA, HMG-CoA reductase, HMG-CoA synthase 1, HMGCR, HMGCS1, MVA, SREBF2, SREBP2, Statins, acute myelogenous leukemia, cerebral ischemia, dipyridamole, hematologic malignancies, hypercholesterolemia, mevalonate, multiple myeloma, multiple myeloma and AML cell lines, myeloma and AML, normal peripheral blood mononuclear cells, patients, statin, statins, sterol, sterol regulatory element-binding transcription factor 2, tumor
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Author Name
Affiliation
Aleksandra A Pandyra
Princess Margaret Cancer Centre, University of Toronto
Peter J Mullen
Princess Margaret Cancer Centre
Manpreet Kalkat
Princess Margaret Cancer Centre, University of Toronto
Zhihua Li
Princess Margaret Cancer Centre
Suzanne Trudel
Princess Margaret Cancer Centre, University of Toronto
Suzanne Trudel
Princess Margaret Cancer Centre, University of Toronto
Aaron D Schimmer
Princess Margaret Cancer Centre, University of Toronto
Linda Z Penn
Princess Margaret Cancer Centre, University of Toronto
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