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Paper Details

Somatic nuclear mitochondrial DNA insertions are prevalent in the human brain and accumulate over time in fibroblasts.
bioRxiv
0
2023
Numt, Numts, brain Numts, circulating immune cells, cognitive impairment, eukaryotes, fibroblasts, healthy, human, human cells, human fibroblast, human fibroblast model, human post-mitotic tissues, humans, mitochondrial DNA, mtDNA, nuclear genomes, nuclear mitochondrial DNA, patient, patient-derived -mutant cells
Author NameAffiliation
Weichen ZhouUniversity of Michigan Medical School ann arbor
Hans-Ulrich KleinCenter for Translational & Computational Neuroimmunology, Columbia University Irving Medical Center
Hans-Ulrich KleinTaub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Irving Medical Center
Philip L De JagerCenter for Translational & Computational Neuroimmunology, Columbia University Irving Medical Center
Philip L De JagerTaub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Irving Medical Center
Philip L De JagerCenter for Translational & Computational Neuroimmunology, Columbia University Irving Medical Center
Philip L De JagerTaub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Irving Medical Center
David A BennettRush University Medical Center
David A BennettRush University Medical Center
Ryan E MillsUniversity of Michigan Medical School ann arbor
Ryan E MillsUniversity of Michigan Medical School ann arbor
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Release 1.2