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Paper Details

An antibody targeting the N-terminal domain of SARS-CoV-2 disrupts the spike trimer.
J Clin Invest
13
2022
ACE2, B cell receptor, COV2-3434, COVID-19, IGHV1-24 gene, N, NTD, NTD supersite, S protein TI region, S protein trimers, SARS, SARS-CoV, SARS-CoV-2, SARS-CoV-2 S protein, SARS-CoV-2-neutralizing antibodies, angiotensin, angiotensin-converting enzyme 2, human, mice, public B cell clonotype, severe, severe acute respiratory syndrome coronavirus, single B cell, spike (S), spike trimer, trimer interface
Author NameAffiliation
Laura A VanBlargan
Rita E Chen
Rita E ChenWashington University School of Medicine
Robert H Carnahan
Robert H CarnahanVanderbilt University Medical Center
Michael S Diamond
Michael S DiamondWashington University School of Medicine
Michael S DiamondWashington University School of Medicine
Ivelin S Georgiev
Ivelin S GeorgievVanderbilt University Medical Center
James E Crowe
James E CroweVanderbilt University Medical Center
James E CroweVanderbilt University Medical Center
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