11q23, 17q11, 5q31, CD70, CD79B, CDKN2A, CNS lymphomagenesis, EBV, EBV PCNSL, Epstein-Barr virus, HLA, IL1R2, Immunodeficiency-associated primary CNS lymphoma, JAK, M2-macrophage, MYD88, NF1, NOTCH, NOTCH pathway, PCNSL, PIM1, RNA, RNASeq, SIK3, SNVs, SOCS1, STAT, STING, T-regulatory cell, cytotoxic T-, exome, germline, immunodeficiency-associated Epstein-Barr virus- (EBV) positive, mast cell, monocyte, primary CNS lymphomas, protein-coding single nucleotide variants, target motifs, tolerogenic, tumor, viral DNA